Does Tangible Boost work on lenses not coated in Tangible Hydra-PEG?

No! Tangible Boost does not work on lenses that are not coated with Tangible Hydra-PEG. Tangible Boost works by binding to the layer of Tangible Hydra-PEG already present on the lens. If there is no layer of Tangible Hydra-PEG present, then Tangible Boost will not be able to bind.